Welcome to the SONIC Lab

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Hubert H. Lim, Ph.D.

Associate Professor

Institute for Translational Neuroscience Scholar

Department of Biomedical Engineering

Department of Otolaryngology, Head and Neck Surgery

Director of SONIC Lab                                                                  

The goal of the lab is to push the development and translation of neural interfaces and medical technologies from scientific concept into clinical application with close collaboration with clinicians and industry. Initial medical applications focus on treating hearing loss, tinnitus and pain. We utilize a range of invasive and noninvasive technologies and approaches including electrical stimulation, ultrasound imaging and stimulation, EEG, and invasive neural recordings in animals and humans to rapidly push technology into the clinical and consumer realm. All projects in the lab follow the translational process depicted in the schematic below. The lab consists of both animal facilities and human testing space to perform proof-of-concept experiments that can then be developed and tested in pilot human studies, followed by further scientific and translational research to achieve confirmatory clinical trials and commercialization.

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The SONIC Lab is pursuing a range of neural engineering and clinical topics. Please click on the images below for further details on each project.

Please click on research image for further details

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Central Auditory Prostheses

Neural Beamforming for Tinnitus

Enhanced Hearing Aid in Humans

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Neuromodulation of Inflammation and the Immune System

Ultrasound Modulation of Brain and Nerves

New Hearing Technologies

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Encoding-Decoding Neural Activity of the Auditory System

Mapping Cross-Sensory Coding of the Brain

Autonomic & Peripheral Neural Recording and Stimulation

 

NEWS

  • 1/18 - Congratulations SONIC Lab for the new DARPA ElectRx grant to pursue a clinical trial evaluating ultrasound neuromodulation of the spleen to treat rheumatoid arthritis in collaboration with Dr. Erik Peterson's team in the Division of Rheumatic and Autoimmune Diseases in the Medical School. 
     
  • 1/18 - Congratulations SONIC Lab for recently being awarded a DARPA Phase II grant to pursue ultrasound neuromodulation of the immune system for pain treatment with Medtronic (Dr. Sara Offutt's team) and Dr. Bryce Binstadt's lab (Pediatric Rheumatology)
     
  • 12/17 - In collaboration with members of Medtronic, the SONIC lab has submitted an exciting new paper highlighting the effects of ultrasound on the auditory system. Publications
     
  • 12/17 - We welcome two new graduate student members to the SONIC lab, Abby Heiller and Claire Kaiser!
     
  • 12/17 - We welcome a new undergraduate student member to the SONIC lab, James Kerber, who will work with John on ultrasound hearing technologies.
     
  • 11/17 - We welcome a new high school student member to the SONIC lab, Aditya Satish, who will work with Yezih on testing our mSync treatment for tinnitus patients.
     
  • 9/17 - Dr. Lim serves as new Chief Scientific Officer at Neuromod Devices in Dublin, Ireland!
     
  • 8/17 - National Science Foundation funds our "NRT Graduate Training Program in Sensory Science: Optimizing the Information for Mind and Brain" led by Dr. Victoria Interrante and affiliated with CCS and CATSS.